We are pleased to announce our latest publication in Journal of Hazardous Materials Advances.
🔬 We investigated the toxicity and intracellular fate of silver nanoparticles present in the food additive E174, commonly used as a decorative coating on confectionery products. Using a human intestinal cell model and advanced electron microscopy techniques, we showed (1) that these nanoparticles can enter intestinal cells and were mainly observed in endo-/autolysosomes, (2) induce cellular stress responses in a concentration-dependent manner, and (3) affect mitochondrial structure and function.
❗Our findings provide new insights into how food-grade silver nanoparticles interact with biological systems. This research highlights the need for comprehensive safety assessments of nanomaterials present in food applications.
📖 Read the publication: Toxicity and fate of silver nanoparticles from the food additive E174: Mitochondrial dynamics underlie their effects in intestinal epithelial cells (https://www.sciencedirect.com/science/article/pii/S2772416626002457)